Intralesional Steroid Injections

Intralesional steroid injections are a dermatology treatment in which small doses of corticosteroids are injected directly into a skin lesion. This allows the medication to act locally, reducing inflammation, controlling abnormal tissue growth and improving skin appearance. 

This treatment is commonly used for conditions such as keloids, hypertrophic scars, cystic acne nodules and persistent inflammatory skin lesions. By delivering medication directly into the affected area, intralesional steroid injections provide precise, targeted therapy while minimising systemic side effects.

Unlike oral steroids, which circulate throughout the body, intralesional injections concentrate the treatment on the site of concern. This improves effectiveness while lowering the risk of side effects commonly associated with systemic steroid use.

How do Intralesional Injections work?

The procedure is a simple process that takes place in an in-clinic setting. Its effects include:

• Targeted anti-inflammatory effect – the corticosteroid suppresses immune activity locally, reducing redness, swelling and pain.
• Collagen modulation – in raised scars, such as keloids or hypertrophic scars, the steroid helps slow excess collagen production, allowing the scar to soften and flatten over time.
• Gradual improvement – changes occur progressively over time. With repeated injections, lesions may become smaller, less firm and less noticeable.

Intralesional steroid injections are suitable for a variety of dermatological concerns. These include:

• Keloids and hypertrophic scars – raised, firm scars that may be itchy, painful or progressively enlarging can be softened and flattened over multiple sessions.
• Cystic acne lesions – large, inflamed nodules respond quickly, reducing redness, swelling and pain.
• Inflammatory skin conditions – certain persistent plaques or nodules, or localised dermatitis, can benefit from steroid injections when topical treatments are insufficient.

What are the benefits of Intralesional Steroid Injections?

The treatment offers several benefits, including:

Clinical benefits

• Reduces inflammation, itching and discomfort quickly
• Improves scar texture, thickness and colour
• Helps soften raised scars and flatten keloids
• Can prevent further growth of keloids and hypertrophic scars

Targeted and controlled treatment

• Delivers medication directly to the affected area
• Allows precise dose control for optimal results
• Minimises systemic steroid exposure compared to oral treatment
• Can be safely repeated under medical supervision

Convenience and recovery

• Quick, in-clinic procedure
• Minimal downtime with no disruption to daily activities

What can I expect from an Intralesional Steroid Injection?

Intralesional steroid injection is a quick, low-risk and simple procedure when it is performed by an experienced dermatologist. 

Before the session

The size, depth and activity of the lesions are examined. Our dermatologist will explain the procedure, expected results and possible side effects of the treatment.

During the session

The treatment area is cleaned thoroughly. The steroid is then injected directly into the lesion using a fine needle. Most patients feel only mild discomfort, such as a brief sting or pressure.

After the session

Mild bruising, redness or swelling may occur at the injection site. Temporary lightening or darkening of the skin can occur as well. Normal activities can usually be resumed immediately after the procedure.

What results can I expect from Intralesional Steroid Injections?

Improvement is gradual and varies depending on the type and size of the lesion. Multiple sessions are usually required. Raised scars may become progressively flatter, softer and less red.

Inflamed acne nodules or localised plaques often shrink quickly, with redness and pain reducing within days.

As response varies between individuals, follow-up visits are important to monitor progress and adjust treatment plans accordingly.

How many sessions are needed?

The treatment frequency depends on the condition and response. It usually entails:

• Keloids and hypertrophic scars – often require 3 to 6 sessions that are spaced between 4 and 6 weeks apart.
• Cystic acne lesions – many respond after a single session.
• Other inflammatory lesions – multiple treatments may be needed for optimal control.